Modafinil vs Adrafinil: A Side by Side Comparison

modafinil vs adrafinil Product Guide

The need to stay fresh, active, and concentrated throughout the day makes people look for some “doping”. For many years people use Modafinil and Adrafinil for these purposes. Both drugs are known as eugeroics, which means that they help to promote wakefulness, let you stay focused and be highly productive during the day.

But what’s the difference between the two? What makes them similar and what is different about them? We hope to give answers to these questions further in our Modafinil – Adrafinil reviews.

A Brief History of Adrafinil

Adrafinil stimulating qualities were discovered by accident. It happened in 1974, in France. Trying to find new analgesics, the chemists of Laboratories Lafon tested various compounds and when the turn came to adrafinil, they noticed the wakefulness-promoting effect of the substance.


Further studies showed that the drug could help people suffering from narcolepsy cope with daytime sleepiness. In 1984 Adrafinil got to the shelves of the French drugstores under the brand name Olmifon. The brand drug is no longer produced since 2011, but you can still buy adrafinil generic online.

Guide to Buying Modafinil and Adrafinil Online

The difficulties associated with buying Modafinil and Adrafinil are based on the legal statuses of these preparations. Modafinil is a prescription-only drug, so it is impossible to buy it without a prescription in any regular drugstore.

Buying Modafinil

Speaking about Adrafinil, the situation is still more difficult. The main question here is “Is Adrafinil legal?”. The answer is “No”. Adrafinil doesn’t have an FDA-approval, and it is impossible to buy it any other way except for from online vendors.

You can find a list of the most reliable online vendors selling both Adrafinil vs Modafinil online on our website. You can choose any of them to buy online without a prescription.

Adrafinil vs Modafinil Dosage

There’s only one Adrafinil dosage strength available – 300 mg. It is recommended to take the drug right after you get up to prevent sleepiness and get an energy boost. The safe doses of Adrafinil are up to 900 mg a day, which is a maximum of three tablets.

Dosage pills

Speaking about Modafinil, this drug can be purchased in 100 mg or 200 mg dosage strengths. The recommended daily dose of the drug is one 200 mg pill in the morning or about an hour before going to work. However, even higher doses of the medication appear to be safe. Still, a maximum daily dose shouldn’t exceed 600 mg.

The fact that the lower doses of Modafinil can be as effective as higher doses of Adrafinil prove the benefits of Modafinil vs Adrafinil. Such a tendency is not surprising as Modafinil drug can be called an improved version of Adrafinil.

The researches show that the effectiveness and the duration of Modafinil and Adrafinil effects depend on the dose of the drug used. Higher doses increase the nootropic effects induced by these medications. However, to be able to sleep well at night, it is important to stick to the recommended dosing regimen.

Adrafinil and Modafinil: Differences

Difference 1. The onset of action.

Unlike Modafinil, which starts working about 20 minutes to an hour after you take the pill, Adrafinil needs more time. The reason is that Adrafinil is a prodrug. To come into effect it needs to be metabolized by the liver into modafinil and modafinil acid. Only after this process is over, the drug starts working, and you can feel the effect of Adrafinil.

Difference 2. Duration of action.

The difference in the onset of action brings about the question of how long does Adrafinil last. In fact, the active substances of both drugs are identical. However, you should keep in mind that Adrafinil needs more time to start acting.

It is considered that the peak effect of the medication can be felt within 5 hours after the intake. Still, the period of maximum efficiency is not the period of drug clearance from the organism. Unlike Modafinil, which can be excreted within 8 hours, Adrafinil can stay in the body for up to 12 hours thus increasing the risks for side effects.

Difference 3. Impact on the liver.

Because of the need to convert Adrafinil to Modafinil, the load on the liver grows. Therefore, continuous intake of Adrafinil can bring much more harm to this organ if compared to Modafinil. If you plan to use a nootropic daily or for an extended period of time, then you should better choose Modafinil.

Difference 4. Side effects.

In general, Adrafinil side effects are similar to those of Modafinil. They are:

  • Headache;
  • Trouble sleeping;

However, the unwanted reactions associated with Adrafinil intake are more numerous and comprise increased liver enzymes count (the issue we’ve talked about earlier) and loss of appetite. The latter can be especially dangerous. Adrafinil weight loss together with increased physical and mental activity promoted by the stimulatory properties of the drug can result in physical and mental exhaustion. Of course, such consequences are possible if the medication is taken on a regular basis.

More about Adrafinil and Modafinil

Modafinil, sold under the brand name Provigil, is a popular nootropic used by college students, air traffic controllers, the military, and people of other professions demanding maximum concentration, endurance, and efficiency.


It is quite safe and is not likely to cause dependence. Modafinil is an instrument that allows people to be the best in their sphere. This drug can become a strong shoulder that can support you when you are emotionally and physically tired.

Adrafinil, Modafinil’s elder brother, is a medication that continues to lose its positions, leaving them to the new generation of more effective and safe nootropics. Armodafinil, being one of them, gains the leadership. Containing only R-enantiomers of racemic modafinil, this drug stays effective longer and tends to be more effective throughout the day if compared to Adrafinil or Modafinil.

The results of the opposition between Armodafinil vs Adrafinil are clear. The latter loses the battle.

Which Is Right for You?

The criteria for the choice of a nootropic drug are similar for most people. Let’s list them and check which of the two drugs matches them better.

  • The nootropic effects of both medicines are based on modafinil. Therefore, they are equal at this point.
  • Swiftness of the effects. Modafinil needs 20 – 60 minutes to start working. Adrafinil effects will make you wait longer. Being a prodrug it needs additional time to be converted into modafinil, which delays the onset of its action to an hour or two. So this point is definitely for Modafinil.
  • Duration of action. Adrafinil stays in the human organism longer than Modafinil, but the maximum effect of the drug is reached 5 hours after the intake, which is similar to the figures demonstrated by Modafinil. So, again, Modafinil wins.
  • The cost of the medication is among the decisive factors for many consumers. Both Modafinil and Adrafinil are available as generics. Also, when you buy Adrafinil, Modafinil, or any other nootropic online, you can save a decent sum of money. Still, generic Adrafinil online is cheaper than generic Modafinil. Now the leadership goes to Adrafinil.

Key Findings: Buying Modafinil and Adrafinil

There’s no doubt as to the wakefulness-promoting and concentration-boosting effects of either of the drugs we are now talking about. However, the severity and the potential negative influence of their side effects encourage us to choose Modafinil instead of its predecessor.

Yet not everyone can afford to buy generic Modafinil, let alone its brand counterpart. That’s where the choice becomes difficult: either a few side effects, high effectiveness, and the high price of Modafinil or a bit more unwanted reactions, high effectiveness, and lower price of Adrafinil. The choice is up to you.

Choosing the right drug is not so easy as you see, and you should think everything over and consider all the pros and cons of both medicines before making a purchase. It is also preferable to consult a doctor before making a choice. Anyway, a specialist may have some other strong arguments in favor of Modafinil or Adrafinil.

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